Thomas Jefferson University Hospital
 
PATIENT & VISITOR INFO

Directions to Center City & Jefferson Hospital for Neuroscience

Jefferson Hospital - Center City
111 South 11th Street
Philadelphia, PA 19107
Jefferson Hospital for Neuroscience
900 Walnut Street
Philadelphia, PA 19107
 The hospitals are easily accessible by car or public transportation.

By Public Transportation

From Northeast Philadelphia

From South Philadelphia

From West Philadelphia

From the suburbs

  • Call SEPTA at 215-580-7800 to determine the regional rail line closest to your home.
  • Take the train to the Market East Station at 11th and Market Streets.

From New Jersey

  By Car

From the Betsy Ross Bridge and points Northeast of Philadelphia

  • Take I-95 South to Exit 22 (Central Philadelphia/Independence Hall/Callowhill Street).
  • At the end of the ramp, turn right onto Callowhill Street.
  • Continue on Callowhill Street to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.
 

From points North and West of Philadelphia (76 East)

  • Take PA Turnpike to Exit 326 (Valley Forge).
  • Take 76 East (Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Philadelphia/676 East) - a leftlane exit
  • Take the Broad Street Exit - a right-lane exit.
  • Get into left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From Northeast Extension of the Pennsylvania Turnpike (Route 476)

  • Take Exit 20 and follow signs for Route 476. Take Route 476 to Exit 16A; then take Route 76 East (Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Phila/676 East) - a left-lane exit.
  • Take the Broad Street Exit - a right-lane exit.
  • Get into left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From Route 309

  • Take Route 309 South to the end of the expressway.
  • Turn left onto Cheltenham Avenue to Route 611 (Broad Street).
  • Turn right onto Route 611 South (Broad Street).
  • Continue on Broad Street (approximately six miles) to Vine Street.
  • Turn left onto Vine Street (outside lane) and follow to 10th Street.
  • Turn right onto 10th Street.
  • Follow 10th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map. 

From Delaware and points South of Philadelphia

  • Take Rt. I-95 North to Exit 22 (Central Phila./Independence Hall/Callowhill St.) - a left-lane exit.
  • Stay in right lane and exit onto Callowhill Street.
  • Once on Callowhill Street, stay in middle lane and continue to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From the Main Line

  • Take Route 476 North to exit 16A (Route 76 East/Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Phila/676 East) - a left-lane exit.
  • Take the Broad Street Exit - a right-lane exit.
  • Stay in left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From New Jersey via Walt Whitman Bridge

  • Cross Walt Whitman Bridge. After the toll booth, take I-95 North to Exit 22 (Central Phila./Independence Hall/Callowhill St.) - left-lane exit.
  • At the end of the ramp, turn right onto Callowhill Street.
  • Once on Callowhill Street, stay in middle lane and continue to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right
  • Follow 11th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From New Jersey via the Ben Franklin Bridge

  • Take bridge and stay in left lane and turn left on 8th Street.
  • Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.

From New Jersey Turnpike

  • Take Exit 4 (73 West) off NJ Turnpike.
  • Follow 73 West to 38 West.
  • Continue on 38 West, following signs for the Ben Franklin Bridge. (38 West will turn into Admiral Wilson Blvd.) Continue to bridge.
  • Take bridge and stay in left lane and turn left on 8th Street.
  • Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson’s campus. Consult the  parking guide for a list of parking locations (including valet parking) and a campus map.